Today I would like to cover the high costs of doing electron microscopy
And this is important because when the conduct of electron microscopy is no longer price competitive with other analytical methods, either microscopic or non-microscopic, less EM works gets done. And that means there are fewer people employed to do EM work.
For at least the last ten years I have heard, especially when standing in our exhibit booth at trade shows, story after story about TEM labs being closed down, mainly in the life sciences area but also in the materials sciences. I invariably hear about the “high cost of doing electron microscopy relative to other techniques”. The shut downs are always blamed on hapless “bean counting” administrators. But is it really?
I for one don’t believe it has to be that way.
In our own laboratory some years ago, when we implemented a “Total Quality Management” system, which in the 1990’s was the management “buzz” word of the decade, we were quite shocked to see how many samples had to be run over again because they were not done right the first time. The quality professionals call this the “cost of rework”. Quite frankly, I was shocked to find out how much money was being wasted because we had not done our work properly the first time. Now I do know that EM work is delicate and all kinds of things can potentially go “wrong”. But once we started keeping track of the different kinds of reasons why the samples were not done right the first time, so that we could learn from our mistakes and reduce the number of instances where such mistakes happened, we were able to reduce the cost of “rework” dramatically.
I know that from time to time there are symposia on “laboratory management” but at least those I have myself attended, they seemed to focus on bringing in money to the laboratory, either by way of increased grant writing or even soliciting work from commercial firms (I will have more to say about this later in some future blog posting).
To me, the real meaning of laboratory management is the managing of the way samples flow through the laboratory and the way human resources are allocated for handling the sample flow. And this all has to be done from the perspective of meeting or exceeding customer and/or client expectations. This means building into each step of each procedure or protocol, a stop-and-look step, to see what could possibly go wrong, and then take some action to make sure it does not happen. And the samples won’t have to be run over again.
This is not the first time I have expressed these thoughts to a TEM audience, though in the past the audience size was far smaller. Some typical responses: “You could never apply TQM in a research laboratory setting.” “It is not the same as manufacturing widgets to some standard specification.” ” I think professionals generally don’t like someone else looking over their shoulder.” But having someone review the reasons why samples had to be done over again, and why they were not done right the first time does not to me seem to be the kind of onerous situation that should get someone upset.
In order to reduce the cost of doing TEM work, we need better management in the laboratory. The skills needed for the proper management of an EM laboratory are no less important than the skills needed for the writing of proposals for funding for the laboratory.





